KMO welcomes 1491 author Charles Mann to the program to talk about the economic, political, sociological, and perhaps most important, biological homogenization that began when Admiral Cristóbal Colón established the first European outpost in what is now the Dominican Republic. This so-called Columbian Exchange initiated a bonanza in global trade which lead to the first global economic crisis. Is that cat out of the bag, or is there still something to be gained by trying to put the breaks on this global free-for-all.

Music by Woodland5.